4th State MedicalRegenerative · Technology
Peer-Reviewed Publications

Clinical Evaluation of the Efficacy of a Topical Acne Product in Improving Skin Conditions

Single-center 30-day clinical study (n=15, ages 18–43) of a topical acne product combining stem cell–conditioned media with salicylic acid. Analysis showed a statistically significant improvement in overall acne lesion appearance from baseline at day 30 (p=0.004) and strong participant-reported improvements in skin texture, with a favorable safety profile.

Date
2024-11-07
Source
Am J Biomed Sci & Res. 2024;24(4)
Authors
5
Topics
2
Abstract

Single-center 30-day clinical study (n=15, ages 18–43) of a topical acne product combining stem cell–conditioned media with salicylic acid. Analysis showed a statistically significant improvement in overall acne lesion appearance from baseline at day 30 (p=0.004) and strong participant-reported improvements in skin texture, with a favorable safety profile.

Authors
Jonathan R.T. Lakey, PhDKrista CasazzaTony AlfiereIan JenkinsMichael Alexander
Citation
Lakey JRT, Casazza K, Alfiere T, Jenkins I, Alexander M. Clinical Evaluation of the Efficacy of a Topical Acne Product in Improving Skin Conditions. Am J Biomed Sci & Res. 2024;24(4) AJBSR.MS.ID.003230.
DOI: 10.34297/AJBSR.2024.24.003230
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2024-10-23
Peer-Reviewed Publications
Reduction in Age-Related Skin Damage Using Products Incorporating Novel Topical Human Mesenchymal Stem Cell Conditioned Media
Jonathan R.T. Lakey, PhD, David Whaley, Tony Alfiere, Ian Jenkins, Michael Alexander · Am J Biomed Sci & Res. 2024;24(3)

Pilot clinical trial (n=12) evaluating a topical stem cell–conditioned skin cream applied over eight weeks to address age-related skin concerns including tone, texture, brightness, and fine lines. Discussion covers the biology of skin senescence, paracrine signaling by MSCs, and the growth-factor and cytokine cargo underlying observed improvements in skin aesthetics.

#MSC#Skin Aging#Cosmeceutical#Microneedling
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